Mounting Evidence in Neuroprotection- Psilocin demonstrates exciting therapeutic promise.

Posted inALS, Psilocin
Recent scientific studies underscore the potential of psilocin to drive transformative neuroprotective effects by promoting neuroplasticity, reducing inflammation, and modulating microglial function, These findings open avenues for research into ALS and other neurodegenerative diseases, where overlapping mechanisms like oxidative stress and neuronal damage are central to disease progression. At Haim Pharma, we’re leveraging these insights to develop stable, disease-specific psilocin formulations that aim to redefine treatment strategies for neurodegenerative conditions. Note: This post is for informational purposes only and does not constitute medical advice.

A Major Breakthrough in ALS Treatment: Qalsody Brings New Hope

Posted inALS, New Treatments
The recent success of Qalsody (tofersen), a treatment targeting the SOD1 mutation in ALS patients, represents a significant leap forward in the fight against this devastating disease. By directly reducing the toxic buildup of SOD1 protein, Qalsody slows the progression of ALS in patients with this specific genetic mutation, improving their survival and quality of life.This progress is a game-changer for ALS research. It demonstrates the power of precision medicine to address specific genetic mutations, offering a glimpse of what’s possible for other forms of ALS. Treatments like Qalsody pave the way for exploring therapies that target different genetic and…

What is ALS

Posted inALS
Amyotrophic Lateral Sclerosis (ALS), is a devastating neurodegenerative disorder, overlapping with Fronto-temporal Dementia (FTD), and is part of a series of syndromes defined as Motor Neuron Diseases (MND) that is characterized by the progressive loss of motor neurons in the brain and spinal cord[1]. The exact pathology is still unclear, but mechanisms such as mitochondrial dysfunction, oxidative stress, inflammation, and glutamate overload are thought to contribute to neuronal loss[2]. ALS is classified based on the initial symptoms: Limb-Onset ALS, and Bulbar-Onset ALS. Over time, ALS often progresses to involve both limb and bulbar regions, causing widespread motor function issues. The…

ALS TDI Summit 2023

Posted inALS
A word from one of our collaborators https://www.youtube.com/watch?t=619&v=D7F8NZQzaMg&feature=youtu.be

Amyotrophic Lateral Sclerosis

Posted inALS
Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive disease with no known cure. It is a neurodegenerative disease, where inflammation and oxidative stress result in the death of neurons. The current treatments do not cure the disease, they only provide a moderate improvement in the symptoms.Cannabinoids and terpenes have repeatedly demonstrated their anti-oxidative, anti-inflammatory, and neuroprotective properties. Based on in silico studies and published scientific research, we are creating a combination of non-psychoactive cannabinoids. This combination should* provide substantial relief from the ALS symptoms while slowing disease progression.This cannabinoid formulation will provide a more effective solution to the current cannabinoid-based…